抗CINC-2α抗体(Anti-CINC-2α, Rat, Goat-Poly, Biotin antibody)

• 価格
• Product Details
• Applications and Data
• Related Research Areas
• Related Product & Information
• Citations

価格

目次に戻る

Product Details

Species Reactivity	Rat
Label	Biotin
Immunogen	E. coli-derived recombinant rat CXCL3/CINC-2 alpha / beta Arg33-Ser100Accession # Q10746
Source	Polyclonal Goat IgG
Purification	Antigen Affinity-purified
Specificity	Detects rat CXCL3/CINC-2 alpha / beta in ELISAs and Western blots. In sandwich immunoassays, approximately 30% cross‑reactivity with recombinant rat (rr) CINC-3 is observed and less than 0.1% cross‑reactivity with rrCINC-1, recombinant mouse (rm) KC, rmMIP-2, and recombinant human GRO alpha is observed.

目次に戻る

Applications and Data

	Recommended Concentration	Sample
Western Blot	0.1 µg/mL	Recombinant Rat CXCL3/CINC-2 alpha (Catalog # 516-CA) Recombinant Rat CXCL3/CINC-2 beta (Catalog # 517-CB)
Rat CXCL3/CINC-2 alpha / beta Sandwich Immunoassay	Reagent
ELISA Capture (Matched Antibody Pair)	2-8 µg/mL	Rat CXCL3/CINC-2 alpha / beta Antibody (Catalog #MAB516 )
ELISA Detection (Matched Antibody Pair)	0.1-0.4 µg/mL	Rat CXCL3/GRO gamma/CINC-2/DCIP-1 Biotinylated Antibody (Catalog #BAF516 )
ELISA Standard		Recombinant Rat CXCL3/CINC-2 alpha Protein (Catalog #516-CA )
Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website.		Preparation and Storage
Reconstitution	Reconstitute at 0.2 mg/mL in sterile PBS.	Reconstitution Buffer Available
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CXCL3/GRO gamma/CINC-2/DCIP-1	CINC-2 alpha and -2 beta are mRNA splice variant isoforms that differ by only 3amino acids at their amino-termini. These proteins are CXC chemokinesmost closely related to human GROs and mouse MIP-2. They are producedby granulation tissue, activated macrophages and fibroblasts. CINC-2biological activities are mediated by CXCR1 or CXCR2.
Entrez Gene IDs:	2921 (Human); 330122 (Mouse); 171551 (Rat)
Alternate Names:	chemokine (C-X-C motif) ligand 3; CINC-2; CINC-2b; C-X-C motif chemokine 3; CXCL3; Dcip1; Gm1960; GRO gamma; GRO3 oncogene; GRO3; GROG; GRO-gamma; GRO-gamma(1-73); Growth-regulated protein gamma; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2B; MIP-2b; MIP2-beta; SCYB3

目次に戻る

Related Research Areas

Chemokines and Receptors in Angiogenesis

CXC Chemokines and Receptors

Inflammatory Mediators

Macrophage Activation Markers

Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines. Authors: Miura TA, Wang J, Holmes KV, Mason RJ Virology, 2007;369(2):288-98. Species: Rat Sample Type: Cell Culture Supernates Application: ELISA Development

目次に戻る

Related Product & Information

Background	CXCL3/GRO gamma/CINC-2/DCIP-1
background_content	Background: CXCL3/GRO gamma/CINC-2/DCIP-1 CINC-2 alpha and -2 beta are mRNA splice variant isoforms that differ by only 3 amino acids at their amino-termini. These proteins are CXC chemokines most closely related to human GROs and mouse MIP-2. They are produced by granulation tissue, activated macrophages and fibroblasts. CINC-2 biological activities are mediated by CXCR1 or CXCR2.

目次に戻る

Citations

1. Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines.
   Authors: Miura TA, Wang J, Holmes KV, Mason RJ
   Virology, 2007;369(2):288-98.
   Species: Rat
   Sample Type: Cell Culture Supernates
   Application: ELISA Development

目次に戻る