抗Galectin-7抗体(Anti-Galectin-7, Goat-Poly antibody)
掲載日情報:2019/10/21 現在Webページ番号:26902
Galectin-7に対する抗体(Anti-Galectin-7, Goat-Poly )です。
※ 本製品は研究用です。研究用以外には使用できません。
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価格
[在庫・価格 :2024年05月07日 19時15分現在]
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Anti-Galectin-7, Goat-Poly |
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Anti-Mouse Galectin-7 Affinity Purified Polyclonal Ab |
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[在庫・価格 :2024年05月07日 19時15分現在]
Anti-Galectin-7, Goat-Poly
文献数: 3
- 商品コード:AF1304
- メーカー:RSD
- 包装:100μg
- 価格:¥100,000
- 在庫:無(未発注)
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
説明文 |
別名:Gal-7 Genbank No: 3963 Protein Accession No: AAK29385 |
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別包装品 | 別包装品あり | ||||||
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保存条件 | -20℃ | 法規備考 | |||||
抗原種 | Mouse | 免疫動物 | Goat | ||||
交差性 | Mouse | 適用 | IHC,Western Blot | ||||
標識 | Unlabeled | 性状 | Antigen Affinity Purified | ||||
吸収処理 | クラス | IgG | |||||
クロナリティ | Polyclonal | フォーマット | |||||
掲載カタログ |
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製品記事 |
免疫染色システム ImmPRESS® Reagent Anti-Goat IgG R&D Systems社のGalectin-7関連製品 |
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関連記事 |
Anti-Mouse Galectin-7 Affinity Purified Polyclonal Ab
文献数: 0
- 商品コード:AF1304-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥30,000
- 在庫:無(未発注)
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
説明文 |
※受注発注品。形状:溶液または凍結乾燥 別名:Gal-7 Genbank No: 3963 Protein Accession No: AAK29385 |
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別包装品 | 別包装品あり | ||||||
法規制等 | |||||||
保存条件 | 法規備考 | ||||||
抗原種 | 免疫動物 | Goat | |||||
交差性 | Mouse | 適用 | IHC,Western Blot | ||||
標識 | Unlabeled | 性状 | Antigen Affinity Purified | ||||
吸収処理 | クラス | IgG | |||||
クロナリティ | Polyclonal | フォーマット | |||||
掲載カタログ |
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製品記事 |
免疫染色システム ImmPRESS® Reagent Anti-Goat IgG |
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関連記事 |
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Product Details
Species Reactivity | Mouse |
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Label | Unconjugated |
Immunogen | E. coli-derived recombinant mouse Galectin‑7Ser2-Phe136Accession # AAK29385 |
Source | Polyclonal Goat IgG |
Purification | Antigen Affinity-purified |
Specificity | Detects mouse Galectin-7 in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross‑reactivity with recombinant human Galectin-7 is observed and less than 1% cross-reactivity with recombinant mouse (rm) Galectin-1, rmGalectin-3, recombinant human (rh) Galectin-8, and rhGalectin-2 is observed. |
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Applications and Data
Recommended Concentration | Sample | |
Western Blot | 0.1 µg/mL | Recombinant Mouse Galectin‑7 (Catalog # 1304-GA) |
Immunohistochemistry | 5-15 µg/mL | Perfusion fixed frozen sections of mouse skin |
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Related Product & Information
Entrez Gene IDs | 3963 (Human); 16858 (Mouse) |
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Background | Galectin-7 |
background_content | Background: Galectin-7 The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. At least 14 mammalian galectins, which share structural similarities in their carbohydrate recognition domains (CRD), have been identified. The galectins have been classified into the prototype galectins (-1, -2, -5, -7, -10, -11, -13, -14), which contain one CRD and exist either as a monomer or a noncovalent homodimer; the chimera galectins (Galectin-3) containing one CRD linked to a nonlectin domain; and the tandem-repeat galectins (-4, -6, -8, -9, -12) consisting of two CRDs joined by a linker peptide. Galectins lack a classical signal peptide and can be localized to the cytosolic compartments where they have intracellular functions. However, via one or more as yet unidentified non-classical secretory pathways, galectins can also be secreted to function extracellularly. Individual members of the galectin family have different tissue distribution profiles and exhibit subtle differences in their carbohydrate-binding specificities. Each family member may preferentially bind to a unique subset of cell-surface glycoproteins (1‑4). Mouse Galectin-7 is a prototype monomeric galectin. It is expressed in stratified epithelia and is significantly down-regulated in squamous cell carcinomas. Galectin-7 is a pro-apoptotic protein that is highly induced by the tumor suppressor protein p53. It functions intracellularly upstream of JNK activation to enhance cytochrome c release during apoptosis (5). Galectin-7 may also be involved in cell-cell and cell-matrix interactions and exogenous galectin has been found to accelerate the re‑epithelialization of wounds (6). |
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Citations
- Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer
PLoS ONE, 2016;11(11):e0166731.
Species: Mouse
Sample Type: Whole Tissue
Application: IHC Paraffin-embedded - A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer.
Authors: Labrie M, Vladoiu M, Leclerc B, Grosset A, Gaboury L, Stagg J, St-Pierre Y
PLoS ONE, 2015;10(7):e0131307.
Species: Human
Sample Type: Cell Lysates
Application: WB - Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells.
Authors: Demers M, Rose AA, Grosset AA, Biron-Pain K, Gaboury L, Siegel PM, St-Pierre Y
Am. J. Pathol., 2010;176(6):3023-31.
Species: Mouse
Sample Type: Cell Lysates
Application: WB
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