抗AMACR, Mouse-Mono(UMAB215) UltraMAB抗体 | Anti-AMACR, Mouse-Mono(UMAB215) UltraMAB Antibody

• 価格
• 特長
• 使用例
• 製品情報

価格

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特長

UltraMAB抗体について
OriGene社製品の中でも、特にUltraMAB抗体シリーズは、ヒト組織の免疫染色(IHC)に適した非常に特異性の高いモノクローナル抗体です。抗原にはTrueMAB抗体と同様、組換え体ヒト全長タンパク質を使用しています。1万種類を超えるタンパク質をスポットしたマイクロアレイを用い、標的タンパク質以外の分子との交差反応がないことを確認済みの、癌研究・病理学・解剖学向けの製品です。

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使用例

	Immunohistochemical staining of paraffin-embedded carcinoma of human prostate tissue using anti-AMACR mouse monoclonal antibody. HIER pretreatment was done with 1mM EDTA in 10mM Tris buffer (pH8.0) at 120°C for 2.5 minutes. UM800107 was diluted 1:800 and detection was done with HRP secondary and DAB chromogen. Strong cytoplasmic and membraneous stain was seen in tumor cells.
	Immunohistochemical staining of paraffin-embedded human kidney tissue within the normal limits using anti-AMACR mouse monoclonal antibody. HIER pretreatment was done with 1mM EDTA in 10mM Tris buffer (pH8.0) at 120°C for 2.5 minutes. UM800107 was diluted 1:800 and detection was done with HRP secondary and DAB chromogen. Weak cytoplasmic and membraneous stain was seen in the tubule epithelial cells.
	Immunohistochemical staining of paraffin-embedded carcinoma of human liver tissue using anti-AMACR mouse monoclonal antibody. HIER pretreatment was done with 1mM EDTA in 10mM Tris buffer (pH8.0) at 120°C for 2.5 minutes. UM800107 was diluted 1:800 and detection was done with HRP secondary and DAB chromogen. Strong cytoplasmic and membraneous stain was seen in tumor cells.
	OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-AMACR mouse monoclonal antibody (UM800107). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.(1:100)

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製品情報

Clone Name	UMAB215
Applications	IHC, 10K-CHIP
Recommend Dilution	IHC 1:100~800,
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size	42.2 kDa
Gene Name	Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1
Background	This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].
Synonyms	AMACRD; CBAS4; RACE; RM; P504S
Database Link	NP_055139

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