抗CYP17A1抗体 | Anti-CYP17A1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of HeLa (A), NIH3T3 (B), H9C2 (C), SW13 (D), ES2 (E) whole cell lysates using GTX56294 CYP17A1 antibody.
	IHC-P analysis of formalin fixed human brain tissue section using GTX56294 CYP17A1 antibody.Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)
	ICC/IF analysis of formalin-fixed NIH3T3 cells using GTX56294 CYP17A1 antibody.Red : Primary antibodyBlue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-P
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500 - 1:1000
ICC/IF	1:100 - 1:500
IHC-P	1:100 - 1:200

Not tested in other applications.

Calculated MW	57 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	KLH-conjugated synthetic peptide encompassing a sequence within the center region of CYP17A1. The exact sequence is proprietary.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	cytochrome P450 family 17 subfamily A member 1 , CPT7 , CYP17 , P450C17 , S17AH
Cellular Localization	Membrane
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 1586 CYP17A1 ・ UniProt: P05093 CYP17A1

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Kong ZL et al. Nutrients 2018; 10 (10) Effect of Cistanche Tubulosa Extracts on Male Reproductive Function in Streptozotocin-Nicotinamide-Induced Diabetic Rats.	Application : WB Reactivity : Rat

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