抗Bax [1C1]抗体 | Anti-Bax [1C1] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Kidney Tissue using Bax Mouse Monoclonal Antibody diluted at 1:200.
	Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast Carcinoma Tissue using Bax Mouse Monoclonal Antibody diluted at 1:200.
	Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Testis Tissue using Bax Mouse Monoclonal Antibody diluted at 1:200.

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	1C1
Isotype	IgG1
Application	WB, IHC-P
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW	21 kDa. ( Note )
Specificity/Sensitivity	Bax Mouse Monoclonal Antibody (1C1) detects endogenous levels of BAX

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PROPERTIES

Form	Liquid
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic Peptide of Bax
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Bcl2 Associated X, Apoptosis Regulator , Bcl2L4 , Bax
Background	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 581 ・ UniProt: Q07812

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