抗EPO抗体 | Anti-EPO antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human esophagus tissue using GTX33183 EPO antibody.
	IHC-P analysis of rat liver tissue using GTX33183 EPO antibody.
	IHC-P analysis of human liver damage tissue using GTX33183 EPO antibody.
	WB analysis of various sample lysates using GTX33183 EPO antibody. The signal was developed with ECL plus-Enhanced.Loading : 25ug per laneDilution : 1:500

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500-1:2000
IHC-P	1:100-1:200

Not tested in other applications.

Calculated MW	21 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH7.3, 0.02% sodium azide, 50% glycerol.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	A synthetic peptide of human EPO
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	erythropoietin , DBAL , ECYT5 , EP , MVCD2
Cellular Localization	Secreted
Background	This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
Database	・ Gene ID: 2056 EPO ・ UniProt: P01588 EPO

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Leigh J et al. Can Urol Assoc J 2018; (Epub) Endogenous H2S production deficiencies lead to impaired renal erythropoietin production.	Application : WB Reactivity : Mouse

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