抗Gli1抗体 | Anti-Gli1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of PC3 (A), mouse brain (B), rat brain (C) whole cell lysates using GTX17495 Gli1 antibody.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500 - 1:2000

Not tested in other applications.

Calculated MW	118 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	KLH-conjugated synthetic peptide encompassing a sequence within the center region of Gli1. The exact sequence is proprietary.
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	GLI family zinc finger 1 , GLI , PAPA8
Cellular Localization	Cytoplasm,Nucleus
Background	This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Database	・ Gene ID: 2735 GLI1 ・ UniProt: P08151 GLI1

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Yang JS et al. Oncol Rep 2018; 39 (1) : 383-391 ITR-284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.

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