抗Anti-Mouse CXCL1/GRO alpha/KC/CINC-1 MAb (Clone 48415R)抗体(Anti-Mouse CXCL1/GRO alpha/KC/CINC-1 MAb (Clone 48415R antibody)
掲載日情報:2021/01/28 現在Webページ番号:232692
Anti-Mouse CXCL1/GRO alpha/KC/CINC-1 MAb (Clone 48415R)に対する抗体(Anti-Mouse CXCL1/GRO alpha/KC/CINC-1 MAb (Clone 48415R )です。
※ 本製品は研究用です。研究用以外には使用できません。
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- 価格
- Product Details
- Applications and Data
- Data Examples
- Related Research Areas
- Related Product & Information
価格
[在庫・価格 :2025年12月03日 15時55分現在]
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[在庫・価格 :2025年12月03日 15時55分現在]
Anti-Mouse CXCL1/GRO alpha/KC/CINC-1 MAb (Clone 48415R)
文献数: 0
- 商品コード:MAB453R-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥27,000
- 在庫:無(未発注)
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
| 説明文 | ※受注発注品。 クローン:48415R Genbank No: 14825 Protein Accession No: P12850 |
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| 法規制等 | |||
| 保存条件 | 法規備考 | ||
| 抗原種 | 免疫動物 | Rat | |
| 交差性 | Mouse | 適用 | ELISA,Neutralising,Western Blot |
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Recombinant | フォーマット | |
| 掲載カタログ |
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| 製品記事 | M1/M2 Macrophage Activation Marker 使いっきり抗体 |
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| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Anti-Mouse CXCL1/GRO alpha/KC/CINC-1 MAb (Clone 48415R)
文献数: 0
- 商品コード:MAB453R-100
- メーカー:RSD
- 包装:100μg
- 価格:¥79,000
- 在庫:無(未発注)
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
| 説明文 | クローン:48415R Genbank No: 14825 Protein Accession No: P12850 |
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|---|---|---|---|
| 法規制等 | |||
| 保存条件 | -20℃ | 法規備考 | |
| 抗原種 | 免疫動物 | Rat | |
| 交差性 | Mouse | 適用 | ELISA,Neutralising,Western Blot |
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Recombinant | フォーマット | |
| 掲載カタログ |
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| 製品記事 | M1/M2 Macrophage Activation Marker |
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| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Product Details
| Species Reactivity | Mouse |
|---|---|
| Label | Unconjugated |
| Immunogen | E. coli-derived recombinant mouse CXCL-1/GRO alpha /KC/CINC‑1Arg20-Lys96Accession # P12850 |
| Source | Recombinant Monoclonal Rat IgG2A Clone # 48415R |
| Purification | Protein A or G purified from cell culture supernatant |
| Specificity | Detects mouse CXCL-1/GRO alpha /KC/CINC‑1 in direct ELISAs. |
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Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 1 µg/mL | Recombinant Mouse CXCL1/GRO alpha /KC/CINC‑1 aa 20-96 (Catalog # 453-KC) |
| Mouse CXCL1/KC Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Mouse CXCL1/GRO alpha /KC/CINC‑1 Antibody (Catalog #MAB453R ) |
| ELISA Detection (Matched Antibody Pair) | 0.1-0.4 µg/mL | Mouse CXCL1/GRO alpha /KC/CINC‑1 Biotinylated Antibody (Catalog #BAF453 ) |
| ELISA Standard | Recombinant Mouse CXCL1/KC Protein (Catalog #453-KC ) | |
| Neutralization | Measured by its ability to neutralize CXCL1/GRO alpha /KC/CINC‑1-induced chemotaxis in the BaF3 mouse pro‑B cell line transfected with human CXCR2. The Neutralization Dose (ND50) is typically 0.05-0.25 µg/mL in the presence of 30 ng/mL Recombinant Mouse CXCL1/GRO alpha /KC/CINC‑1 aa 20‑96. | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | ||
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Data Examples
| Neutralization |
![]() click image to view larger | Chemotaxis Induced by CXCL1/GRO alpha /KC/CINC-1 and Neutralization by Mouse CXCL1/GRO alpha /KC/CINC-1 Antibody.Recombinant Mouse CXCL1/GRO alpha /KC/CINC-1 aa 20-96 (Catalog # 453-KC) chemoattracts the BaF3 mouse pro-B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CXCL1/GRO alpha /KC/CINC-1 aa 20-96 (30 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CXCL1/GRO alpha /KC/CINC-1 Monoclonal Antibody (Catalog # MAB453R). The ND50 is typically0.05-0.25 µg/mL. |
| Reconstitution | Reconstitute at 0.5 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: CXCL1/GRO alpha/KC/CINC-1 | CXCL1, also known as KC and GRO alpha, is a CXC family chemokine that is expressed in fibroblasts, macrophages, and endothelial cells and interacts with CXCR2. CXCL1 is a potent neutrophil attractant and activator. It also promotes angiogenesis by inducing VEGF production by neutrophils. N-terminally truncated CXCL1 demonstrates increased potency in CXCR2 signaling. Mature mouse CXCL1 shares 96% and 64% aa sequence identity with rat and human CXCL1, respectively. | |
| Entrez Gene IDs: | 2919 (Human); 14825 (Mouse); 81503 (Rat) | |
| Alternate Names: | CINC1; CINC-1; CXCL1; GRO alpha; KC; MGSA-alpha | |
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Related Research Areas
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Related Product & Information
| Entrez Gene IDs | 2919 (Human); 14825 (Mouse); 81503 (Rat) |
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| Background | CXCL1/GRO alpha/KC/CINC-1 |
| background_content | Background: CXCL1/GRO alpha/KC/CINC-1 CXCL1, also known as KC and GRO alpha, is a CXC family chemokine that is expressed in fibroblasts, macrophages, and endothelial cells and interacts with CXCR2. CXCL1 is a potent neutrophil attractant and activator. It also promotes angiogenesis by inducing VEGF production by neutrophils. N-terminally truncated CXCL1 demonstrates increased potency in CXCR2 signaling. Mature mouse CXCL1 shares 96% and 64% aa sequence identity with rat and human CXCL1, respectively. |
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