LysoGlow84™ (CAS: 1782983-52-1)

C₁₆H₁₂N₃ . C₂F₃O₂

• Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects.
• Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). 
• pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440).
• No esterases are involved, therefore no toxic by-products occur.
• Long-term stable; is barely metabolized.
• Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)

1. The chemically synthesized Ageladine A-derivative LysoGlow84 stains lysosomes in viable mammalian brain cells and specific structures in the marine flatworm Macrostomum lignano: T. Mordhorst, et al.; Mar. Drugs 13, 920 (2015)