抗Human CX3CR1 Phycoerythrin抗体(Anti-Human CX3CR1 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	E. coli-derived recombinant human CX3CR1 Met1-Thr31, Leu91-Lys103, Thr168-Thr195, Lys257-Leu273Accession # NP_001328
Source	Monoclonal Mouse IgG1 Clone # 528728
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CX3CR1 in direct ELISAs.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CX3CR1 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CX3CR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB5204P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	CX3C Chemokine Receptor 1
Background	CX3CR1
background_content	Background: CX3CR1 CX3CR1 is a 40 kDa seven transmembrane chemokine receptor that is expressed on several T cell subsets, monocytes, macrophages, microglia, and epithelial cells. CX3CR1 binding to membrane bound or soluble CX3CR1/Fractalkine promotes inflammatory responses by inducing monocyte adhesion to endothelial cells and macrophage activation. CX3CR1 polymorphisms are associated with the development of chronic inflammatory disorders. Alternately spliced isoforms have extended N-terminal extracellular regions that increase the potency of CX3CR1 as a fusion co-receptor for HIV-1. Human CX3CR1 shares 82% amino acid sequence identity with mouse and rat CX3CR1.

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Citations

1. Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis
   Authors: Karoline Walscheid
   Clin. Immunol, 2016;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine/Chemokine Receptor Complex in Patients with AMD.
   Authors: Falk M, Singh A, Faber C, Nissen M, Hviid T, Sorensen T
   PLoS ONE, 2014;9(12):e112473.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph.
   Authors: Carrega, Paolo, Bonaccorsi, Irene, Di Carlo, Emma, Morandi, Barbara, Paul, Petra, Rizzello, Valeria, Cipollone, Giuseppe, Navarra, Giuseppe, Mingari, Maria Cr, Moretta, Lorenzo, Ferlazzo, Guido
   J Immunol, 2014;192(8):3805-15.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Changes of peripheral TGF-beta1 depend on monocytes-derived macrophages in Huntington disease.
   Authors: Di Pardo A, Alberti S, Maglione V, Amico E, Cortes E, Elifani F, Battaglia G, Busceti C, Nicoletti F, Vonsattel J, Squitieri F
   Mol Brain, 2013;6(0):55.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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