抗Beclin 1抗体 | Anti-Beclin 1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IP analysis of HeLa cells using GTX55535 Beclin 1 antibody.IP reaction : 200μg extracts / 3μg antibody antibodyDilution : 1:1000
	WB analysis of various sample lysates using GTX55535 Beclin 1 antibody.Loading : 25ug per laneDilution : 1:1000
	ICC/IF analysis of HeLa cells using GTX55535 Beclin 1 antibody.Blue : DAPIDilution : 1:100
	IHC-P analysis of mouse kidney tissue using GTX55535 Beclin 1 antibody. Dilution : 1:100

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-P, IP
Reactivity	Human, Mouse, Rat, Pig

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500-1:2000
ICC/IF	1:50-1:200
IHC-P	1:50-1:200
IP	1:50-1:100

Not tested in other applications.

Calculated MW	52 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH7.3, 0.02% sodium azide, 50% glycerol.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human BECN1 (NP_003757.1).
Purification	Purified by affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	beclin 1 , ATG6 , VPS30 , beclin1
Cellular Localization	Cytoplasm,Endosome membrane,Endoplasmic reticulum membrane,Endosome,Nucleus
Background	This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Database	・ Gene ID: 8678 BECN1 ・ UniProt: Q14457 BECN1

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Koh EH et al. J Biol Chem 2016; 291 (47) : 24747-24755 Mitochondrial Activity in Human White Adipocytes Is Regulated by the Ubiquitin Carrier Protein 9/microRNA-30a Axis.	Application : WB Reactivity : Human

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