抗Src (phospho Tyr416) (Alexa Fluor 488)抗体 | Anti-Src (phospho Tyr416) (Alexa Fluor 488) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

ICC/IF analysis of MDCK cells were left untreated (A), stimulated with H2O2 (1 mM for 10 minutes) (B), or pretreated with PP2 prior to H2O2 stimulation (C) using GTX54529 Src (phospho Tyr416) antibody (Alexa Fluor 488).

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF
Reactivity	Human, Mouse, Dog, Chicken

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent

Not tested in other applications.

Calculated MW	60 kDa. ( Note )
Specificity/Sensitivity	Based on sequence homology, this antibody may cross with other Src family members such as YES1 , FYN proteins when phosphorylated at the equivalent sites.

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.3, 0.2mg/ml BSA, 0.05% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Immunogen	This antibody was produced against a chemically synthesized phosphopeptide derived from the region of Src that contains tyrosine 416. The antibody was affinity purified by sequential epitope-specific chromatography, then conjugated to Alexa Fluor 488. The Tyr418 of human Src is equivalent to Tyr416 of chicken Src.
Purification	Purified IgG
Conjugation	Alexa Fluor 488
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src
Cellular Localization	Cell membrane,Mitochondrion inner membrane,Nucleus,Cytoplasm, cytoskeleton
Background	This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 6714 SRC ・ UniProt: P12931 SRC

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