抗Bcl2A1抗体 | Anti-Bcl2A1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of mouse kidney tissue using GTX31738 Bcl2A1 antibody. Working concentration : 20 μg/ml
	WB analysis of (A) human kidney and (B) human lung tissue lysate using GTX31738 Bcl2A1 antibody. Working concentration : 1 μg/ml
	IHC-P analysis of mouse kidney tissue using GTX31738 Bcl2A1 antibody. Working concentration : 10 μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1 μg/mL
IHC-P	10 μg/mL
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	20 kDa. ( Note )
Positive Control	Human Lung Tissue Lysate(GTX27917) , Mouse Kidney Tissue Lysate(GTX27936) , Human Kidney Tissue Lysate(GTX29995)
Specificity/Sensitivity	At least two isoforms are known to exist; this antibody will only detect the larger isoform.

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Bcl2A1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Bcl2A1.The immunogen is located within the last 50 amino acids of Bcl2A1.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	BCL2 related protein A1 , ACC-1 , ACC-2 , ACC1 , ACC2 , BCL2L5 , BFL1 , GRS , HBPA1
Cellular Localization	Cytoplasm
Background	This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 597 BCL2A1 ・ UniProt: Q16548 BCL2A1

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