抗CARD10抗体 | Anti-CARD10 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

IHC-P analysis of human kidney tissue using GTX31678 CARD10 antibody. Working concentration : 5 μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P, ELISA
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
IHC-P	5 μg/mL
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	116 kDa. ( Note )
Positive Control	Human Kidney Tissue Slide
Specificity/Sensitivity	This antibody is human specific. At least three isoforms are known to exist; this antibody will only detect isoform 1. This antibody is predicted not to cross-react with other CARMA proteins.

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	CARD10 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CARD10.The immunogen is located within the first 50 amino acids of CARD10.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	caspase recruitment domain family member 10 , BIMP1 , CARMA3
Cellular Localization	Cytoplasm
Background	The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]
Database	・ Gene ID: 29775 CARD10 ・ UniProt: Q9BWT7 CARD10

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