抗Caspase 12抗体 | Anti-Caspase 12 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human mammary cancer tissue using GTX12333 Caspase 12 antibody.
	IHC-P analysis of human lung cancer tissue using GTX12333 Caspase 12 antibody.
	WB analysis of various samples using GTX12333 Caspase 12 antibody.Lane 1 : PANC whole cell lysate at 40ug Lane 2 : SMMC whole cell lysate at 40ug Lane 3 : A549 whole cell lysate at 40ug Lane 4 : HeLa whole cell lysate at 40ug Dilution : 0.5 μg/mL

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.1-0.5μg/ml
IHC-P	0.5-1μg/ml

Not tested in other applications.

Calculated MW	38.87 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	2.5% BSA, 0.45% NaCl, 0.1% Na₂HPO₄, 0.025% Thimerosal, 0.025% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	500 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-12(71-84aa KIFREHLWNSKKQL).
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Background

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011]

Database

・ Gene ID: 100506742 CASP12 ・ UniProt: Q6UXS9 CASP12

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