抗ABCG2抗体 | Anti-ABCG2 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

WB analysis of various samples using GTX12131 ABCG2 antibody.Lane 1 : rat liver tissue lysate at 50ug Lane 2 : rat spleen tissue lysate at 50ug Lane 3 : rat kidney tissue lysate at 50ug Lane 4 : mouse spleen tissue lysate at 50ug Dilution : 0.5 μg/mL

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.1-0.5μg/ml

Not tested in other applications.

Calculated MW	73 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	2.5% BSA, 0.45% NaCl, 0.1% Na₂HPO₄, 0.025% Thimerosal, 0.025% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	500 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Mouse
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of mouse BCRP/ABCG2(152-167aa KNHEKNERINTIIKEL), different from the related rat sequence by one amino acid.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , AI428558 , BCRP , Bcrp1 , MXR , MXR1
Cellular Localization	Cell membrane
Background	The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 26357 Abcg2 ・ UniProt: Q7TMS5 Abcg2

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Garcia-Arroyo FE et al. PLoS One 2018; 13 (8) : e0202901 Probiotic supplements prevented oxonic acid-induced hyperuricemia and renal damage.	Application : WB Reactivity : Rat
Rosen MB et al. Birth Defects Res 2017; (Epub) ATP Binding Cassette Sub-family Member 2 (ABCG2) and Xenobiotic Exposure During Early Mouse Embryonic Stem Cell Differentiation.	Reactivity : Mouse

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