抗TRAIL [55B709.3]抗体 | Anti-TRAIL [55B709.3] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human kidney tissue using GTX12124 TRAIL antibody [55B709.3]. Dilution : 5 μg/ml
	WB analysis of Jurkat cell lysate using GTX12124 TRAIL antibody [55B709.3].

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	55B709.3
Isotype	IgG1
Application	WB, IHC-P
Reactivity	Human, Cat, Dog

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1 - 2 μg/ml
IHC-P	5 μg/ml

Not tested in other applications.

Calculated MW	33 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS, 0.05% BSA, 0.05% Sodium Azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	This monoclonal antibody was raised against a peptide corresponding to amino acids 17-35 of human TRAIL. This peptide sequence has been shown to be involved in TRAIL and DR5 (TRAIL-R2) interaction.
Purification	Protein G purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	TNF superfamily member 10 , APO2L , Apo-2L , CD253 , TL2 , TNLG6A , TRAIL
Cellular Localization	Cell membrane,Secreted
Background	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. [provided by RefSeq]
Database	・ Gene ID: 8743 TNFSF10 ・ UniProt: P50591 TNFSF10

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