抗MITF [C5]抗体 | Anti-MITF [C5] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Immunohistochemical staining using microphthalmia antibody on formalin fixed, paraffin embedded human melanoma.

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	C5
Isotype	IgG1
Application	WB, IHC-P, IHC-Fr, IP, Gel supershift assays
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

For IP: Use at a concentration of 2 μg/ml. For WB: Use at a concentration of 1 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW	59 kDa. ( Note )
Positive Control	501 Mel human melanoma cells and wild-type human, rat or mouse osteoclast cells

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PROPERTIES

Form	Liquid
Buffer	Phosphate-buffered saline containing 0.08% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	N-terminal fragment of human microphthalmia protein and mouse myeloma NS1 cells.
Purification	Protein G purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Melanogenesis Associated Transcription Factor , Cmm8 , Commad , Mi , Ws2 , Ws2A , Bhlhe32 , Mitf
Background	This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
Database	・ Gene ID: 4286 ・ UniProt: O75030

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Kawahara K et al. Glia 2016; 64 (11) : 1938-61 the novel monoclonal antibody 9f5 reveals expression of a fragment of gpnmb/osteo* processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain.	Application : IHC-Fr Reactivity : Mouse, Rat

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