抗N-Cadherin [GC-4]抗体 | Anti-N-Cadherin [GC-4] antibody

• 2025/10/01

  試薬 プレゼント

  [GNT]【数量限定】早いもの勝ち！ジェンタくんキーホルダープレゼントキャンペーン[～2025/10/31]

  期間：2025/10/01 ～2025/10/31

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  GeneTex International Corporation（GNT）

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	GC-4
Isotype	IgG1
Application	WB, ICC/IF, IHC-Fr, FACS, EM
Reactivity	Human, Mouse, Rat, Rabbit, Chicken

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:100
ICC/IF	Assay dependent
IHC-Fr	1:100
FACS	Assay dependent
EM	Assay dependent

Not tested in other applications.

Calculated MW	100 kDa. ( Note )
Positive Control	chicken or rat cardiac muscle

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PROPERTIES

Form	Liquid
Buffer	Ascites, 15 mM sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species	Chicken
Immunogen	Affinity purified chicken heart A-CAM.
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	cadherin 2 , cadherin-2
Cellular Localization	Cell membrane
Background	Monoclonal Anti-N Cadherin/ACAM may be used for the localization of a 135 kDa receptor of the intercellular adherens junction in immunofluorescent microscopy, electron microscopy, and immunoblotting. This antibody can also be used to study the mechanism of adhesion and interaction of cultured cells and cells in tissues.Monoclonal Anti-NCadherin/ACAM stains a large variety of intercellular junctions formed by chicken fibroblastic and epithelial cells in culture. In adult mammals, the antibody stains predominantly heart and lens tissue and also stains a large variety of embryonic tissue. By double labelling, this antibody appears to localize vinculin and actin-rich intercellular contacts and is absent from cellular matrix attachment sites.
Database	・ Gene ID: 414745 CDH2 ・ UniProt: P10288 CDH2

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Kiel MJ et al. Cell Stem Cell 2007; 1 (2):204-17 Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance.	Application : FACS Reactivity : Mouse
Li G et al. Cancer Res 2001; 61 (9):700933 N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells.	Application : ICC/IF Reactivity : Human

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