抗S100A6 [CACY-100]抗体 | Anti-S100A6 [CACY-100] antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	CACY-100
Isotype	IgG1
Application	WB, IHC-P, IHC-Fr, IP
Reactivity	Human, Rat, Goat, Bovine, Dog, Pig, Lizard

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IHC-P	Assay dependent
IHC-Fr	1:4,000
IP	Assay dependent

Not tested in other applications.

Calculated MW	10 kDa. ( Note )
Positive Control	bovine tongue
Specificity/Sensitivity	Recognizes an epitope located on S100A6 (Calcyclin in the old terminology) in a Ca2+ ion-dependent manner. The product does not react with other members of the EF-hand family such as calmodulin, parvalbumin, intestinal calcium-binding protein, S100A2 (S100L), caltropin, the α chain of S-100 (i.e. in S-100a and S-100ao), or the β chain (i.e. in S-100a and S-100b).

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PROPERTIES

Form	Liquid
Buffer	Ascites, 15 mM sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species	Pig
Immunogen	Ca2+-binding proteins from pig stomach tissue
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	S100 calcium binding protein A6 , 2A9 , 5B10 , CABP , CACY , PRA , S10A6
Cellular Localization	Cytoplasm
Background	This protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Database	・ Gene ID: 6277 S100A6 ・ UniProt: P06703 S100A6

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Scheiter M et al. Mol Cell Proteomics 2013; 12 (5) : 1099-114 Proteome analysis of distinct developmental stages of human natural killer (NK) cells.

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