抗HMBS, Mouse-Mono(UMAB144) UltraMAB抗体 | Anti-HMBS, Mouse-Mono(UMAB144) UltraMAB Antibody

掲載日情報:2015/11/06 現在Webページ番号:178131

OriGene社の抗HMBS, Mouse-Mono(UMAB144) UltraMAB抗体です。
本製品は、UltraMAB抗体シリーズ(三次元構造を有する組換え体ヒトタンパク質の全長を抗原として作製したモノクローナル抗体)です。

本製品は研究用です。研究用以外には使用できません。

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[在庫・価格 :2024年05月19日 00時00分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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納期 文献数
Anti-HMBS, Mouse-Mono(UMAB144), UltraMAB
3~4週間 ※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 0
説明文
クローン:UMAB144
Genbank No: 3145
Gene Accession No: NM_000190
法規制等
保存条件 法規備考
抗原種 免疫動物 Mouse クラス IgG 標識 Unlabeled
交差性 Human/Mouse/Rat 適用 IF,IHC,Western Blot
クロナリティ Monoclonal フォーマット 性状 吸収処理
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製品記事 UltraMAB抗体
関連記事

[在庫・価格 :2024年05月19日 00時00分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

Anti-HMBS, Mouse-Mono(UMAB144), UltraMAB

文献数: 0

説明文 クローン:UMAB144
Genbank No: 3145
Gene Accession No: NM_000190
法規制等
保存条件 法規備考
抗原種 免疫動物 Mouse
交差性 Human/Mouse/Rat 適用 IF,IHC,Western Blot
標識 Unlabeled 性状
吸収処理 クラス IgG
クロナリティ Monoclonal フォーマット
掲載カタログ

製品記事 UltraMAB抗体
関連記事

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UltraMAB抗体について

UltraMAB抗体

OriGene社製品の中でも、特にUltraMAB抗体シリーズは、ヒト組織の免疫染色(IHC)に適した非常に特異性の高いモノクローナル抗体です。抗原にはTrueMAB抗体と同様、組換え体ヒト全長タンパク質を使用しています。1万種類を超えるタンパク質をスポットしたマイクロアレイを用い、標的タンパク質以外の分子との交差反応がないことを確認済みの、癌研究・病理学・解剖学向けの製品です。

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Product Data

Immunogen Full length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.
Clone Name Clone UMAB144 Isotype IgG1
Species Reactivity Human Concentration 0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application WB, IHC, IF Suggested Dilutions WB 1:2000, IHC 1:200,
Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

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Reference Data

Target Name Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1
Alternative Name PBG-D; PBGD; PORC; UPS
Database Link NP_000181
Function This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Related Pathway

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Image

Western blot analysis of  HT29 cell lysate (35ug) by using anti-HMBS monoclonal antibody.
Western blot analysis of  K562 cell lysate (35ug) by using anti-HMBS monoclonal antibody.
Western blot analysis of KM12 cell lysate (35ug) by using anti-HMBS monoclonal antibody.
Western blot of human tissue lysates (15ug) from 10 different tissues (1: Testis, 2: Omentum, 3: Uterus, 4: Breast, 5: Brain, 6: Liver, 7: Ovary, 8: Thyroid, 9: Colon, 10: Spleen ). Diluation: 1:500.
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human melanoma tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human muscle tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human embryonic brain cortex tissue using anti-HMBS mouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human embryonic cerebellum using anti-HMBSmouse monoclonal antibody. (UM800041; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded human tonsil using anti-HMBS clone UMAB144 mouse monoclonal antibody at 1:400 with Polink2 Broad HRP DAB detection kit (UM800041); heat-induced epitope retrieval with citrate buffer, pH6.0at 95-100C. Strong cytoplasmic and membraneous staining is seen on tonsil germinal and non-germinal centers. Some weak nuclear stain was also observed.
Immunohistochemical staining of paraffin-embedded human spleen using anti-HMBS clone UMAB144 mouse monoclonal antibody at 1:400 with Polink2 Broad HRP DAB detection kit (UM800041); heat-induced epitope retrieval with citrate buffer, pH6.0at 95-100C. Strong cytoplasmic and membraneous staining is seen on spleen.
Immunohistochemical staining of paraffin-embedded human prostate cancer using anti-HMBS clone UMAB144 mouse monoclonal antibody at 1:400 with Polink2 Broad HRP DAB detection kit (UM800041); heat-induced epitope retrieval with citrate buffer, pH6.0at 95-100C. Weak nuclear staining is seen on tumor cells.
Immunofluorescent staining of HeLa cells using anti-HMBS mouse monoclonal antibody (UM800041, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue). Scale bar, 20µm.

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