抗PARN, Mouse-Mono(UMAB143) UltraMAB抗体 | Anti-PARN, Mouse-Mono(UMAB143) UltraMAB Antibody

• 価格
• UltraMAB抗体について
• Product Data
• Reference Data
• Image

価格

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UltraMAB抗体について

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Product Data

Immunogen	Human recombinant protein fragment corresponding to amino acids 1-266 of human PARN (NP_002573) produced in E.coli.
Clone Name	Clone UMAB143	Isotype	IgG2a
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application	WB, IHC, 10K-CHIP	Suggested Dilutions	WB 1:2000, IHC 1:100~200,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography

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Reference Data

Target Name	Homo sapiens poly(A)-specific ribonuclease (PARN), transcript variant 1
Alternative Name	DAN
Database Link	NP_002573
Function	The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
Related Pathway

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Image

WB Image	Western blot analysis of RPMI8226 cell lysate (35ug) by using anti-PARN monoclonal antibody.
WB Image	Western blot of human tissue lysates (15ug) from 10 different tissues (1: Testis, 2: Omentum, 3: Uterus, 4: Breast, 5: Brain, 6: Liver, 7: Ovary, 8: Thyroid, 9: Colon, 10: Spleen). Diluation: 1:500.
IHC Image	Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PARNmouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PARNmouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PARN mouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human tonsil using anti-PARNmouse monoclonal antibody. (UM800040; heat-induced epitope retrieval by 10mM citric buffer, pH9.0, 120C for 3min)
10K-CHIP Image	OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-PARN mouse monoclonal antibody (UM800040). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.

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