抗PBX1, Mouse-Mono(UMAB111) UltraMAB抗体 | Anti-PBX1, Mouse-Mono(UMAB111) UltraMAB Antibody

• 価格
• UltraMAB抗体について
• Product Data
• Reference Data
• Image

価格

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UltraMAB抗体について

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Product Data

Immunogen	Full length human recombinant protein of human PBX1(NP_002576) produced in HEK293 cell.
Clone Name	Clone Clone UMAB111	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application	IHC, IF, 10K-CHIP	Suggested Dilutions	IHC 1:100~200,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography

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Reference Data

Target Name	Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1
Alternative Name	DKFZp686B09108; MGC126627
Database Link	NP_002576
Function	This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar
Related Pathway

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Image

IHC Image	Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PBX1 mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-PBX1 mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PBX1 mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PBX1mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-PBX1 mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-PBX1 mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Human tonsil using anti-PBX1 mouse monoclonal antibody. (UM500078; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IF Image	Immunofluorescent staining of HeLa cells using anti-PBX1 mouse monoclonal antibody (UM500078, green, 1:50). Actin filaments were labeled with Alexa Fluor® 594 Phalloidin (red), and nuclear with DAPI (blue).
10K-CHIP Image	OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-PBX1 mouse monoclonal antibody (UM500078). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification.

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