抗FOLH1, Mouse-Mono(UMAB25) UltraMAB抗体 | Anti-FOLH1, Mouse-Mono(UMAB25) UltraMAB Antibody

掲載日情報:2015/11/06 現在Webページ番号:177795

OriGene社の抗FOLH1, Mouse-Mono(UMAB25) UltraMAB抗体です。
本製品は、UltraMAB抗体シリーズ(三次元構造を有する組換え体ヒトタンパク質の全長を抗原として作製したモノクローナル抗体)です。

本製品は研究用です。研究用以外には使用できません。

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[在庫・価格 :2024年05月19日 00時00分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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納期 文献数
Anti-FOLH1, Mouse-Mono(UMAB25), UltraMAB
3~4週間 ※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 0
説明文
クローン:UMAB25
Genbank No: 2346
Gene Accession No: NM_004476
法規制等
保存条件 法規備考
抗原種 免疫動物 Mouse クラス IgG 標識 Unlabeled
交差性 Human/Dog/Rat/Monkey/Mouse 適用 IF,IHC,IP,Western Blot
クロナリティ Monoclonal フォーマット 性状 Affinity Purified 吸収処理
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製品記事 UltraMAB抗体
関連記事

[在庫・価格 :2024年05月19日 00時00分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

Anti-FOLH1, Mouse-Mono(UMAB25), UltraMAB

文献数: 0

説明文 クローン:UMAB25
Genbank No: 2346
Gene Accession No: NM_004476
法規制等
保存条件 法規備考
抗原種 免疫動物 Mouse
交差性 Human/Dog/Rat/Monkey/Mouse 適用 IF,IHC,IP,Western Blot
標識 Unlabeled 性状 Affinity Purified
吸収処理 クラス IgG
クロナリティ Monoclonal フォーマット
掲載カタログ

製品記事 UltraMAB抗体
関連記事

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UltraMAB抗体について

UltraMAB抗体

OriGene社製品の中でも、特にUltraMAB抗体シリーズは、ヒト組織の免疫染色(IHC)に適した非常に特異性の高いモノクローナル抗体です。抗原にはTrueMAB抗体と同様、組換え体ヒト全長タンパク質を使用しています。1万種類を超えるタンパク質をスポットしたマイクロアレイを用い、標的タンパク質以外の分子との交差反応がないことを確認済みの、癌研究・病理学・解剖学向けの製品です。

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Product Data

Immunogen Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.
Clone Name Clone UMAB25 Isotype IgG2b
Species Reactivity Human , Dog , Rat , Monkey , Mouse Concentration 0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application WB, IHC, IF, 10K-CHIP Suggested Dilutions WB 1:500~2000, IF 1:100, IF 1:100
Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

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Reference Data

Target Name Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1
Alternative Name FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Database Link NP_004467
Function This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq].
Related Pathway

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Image

Western Blot analysis of 10 different human tissue lysates (10ug) by using anti-FOLH1 monoclonal antibody (clone UMAB25, 1:500)
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded thyroid tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of endometrium tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-FOLH1mouse monoclonal antibody. (Clone UMAB25, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunofluorescent staining of PC-12 cells using FOLH1 mouse monoclonal antibody (UM500025, green). Actin filaments were labeled with TRITC-phalloidin (red), and nuclear with DAPI (blue). The three-color overlay image is located at the bottom-right corner.
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-FOLH1 mouse monoclonal antibody (Clone UMAB25). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-FOLH1 (Clone UMAB25) very specifically recognizes FOLH1 antigen on OriGene protein microarray chip.

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