抗TP53, Mouse-Mono(UMAB18) UltraMAB抗体 | Anti-TP53, Mouse-Mono(UMAB18) UltraMAB Antibody

• 価格
• UltraMAB抗体について
• Product Data
• Reference Data
• Image

価格

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UltraMAB抗体について

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Product Data

Immunogen	Full length human recombinant protein of human TP53 (NP_000537) produced in HEK293T cell.
Clone Name	Clone UMAB18	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application	WB, IHC	Suggested Dilutions	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography

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Reference Data

Target Name	Homo sapiens tumor protein p53 (TP53), transcript variant 1
Alternative Name	BCC7; LFS1; P53; TRP53
Database Link	NP_000537
Function	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq].
Related Pathway

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Image

WB Image	Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TP53 monoclonal antibody (Clone UMAB18).
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-TP53 mouse monoclonal antibody. (Clone UMAB18, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
IHC Image	Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TP53 mouse monoclonal antibody. (Clone UMAB18, dilution 1:100; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

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