Narlaprevir | CAS:865466-24-6

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Name:Narlaprevir; SCH 900518
Cat. No. :CS-0445
CAS No. :865466-24-6
Formula:C36H61N5O7S
M. Wt. : 707.96
Solubility:10 mM in DMSO

Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor(Ki=6 nM; EC90=40 nM)IC50 Value: 6 nM (Ki)Target: HCV NS3/4A Protease; HCVNarlaprevir (SCH 900518) is a potent inhibitor of the hepatitis C virus (HCV) nonstructural protein 3 serine protease that is primarily metabolized by the cytochrome P450-3A4 system. Narlaprevir administration resulted in a robust HCV-RNA decline and high SVR rates when followed by standard of care in both treatment-experienced and treatment-naive HCV genotype 1-infected patients.

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