抗Munc 13-4, Internal抗体 | Anti-Munc 13-4, Internal antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human thymus using GTX89269 Munc 13-4 antibody, Internal. Antigen retrieval : citrate buffer pH 6Dilution : 2.5μg/ml
	IHC-P analysis of mouse lung (wt in A and KO in B) using GTX89269 Munc 13-4 antibody, Internal. Dilution : 0.5μg/ml
	WB analysis of human T-lymphocyte lysate using GTX89269 Munc 13-4 antibody, Internal. Dilution : 2μg/mlLoading : 35μg protein in RIPA buffer

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製品情報

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1-3μg/ml
IHC-P	1-2μg/ml
Note : IHC-P Human Thymus shows cytoplasm staining in select areas.

Not tested in other applications.

Calculated MW	123 kDa. ( Note )
Positive Control	The peptide used to generate this antibody is available for purchase (GTX89269-PEP).
Predict Reactivity	Rat, Bovine, Dog, Pig(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Peptide with sequence C-ETQKHKKDLHPLFD, from the internal region of the protein sequence according to NP_954712.1.
Purification	Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Unc-13 Homolog D , Fhl3 , Hlh3 , Hplh3 , Munc13-4 , Unc13D
Cellular Localization	Colocalizes with cytotoxic granules at the plasma membrane. Localizes to endosomal exocytic vesicles.
Background	This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 201294 ・ UniProt: Q70J99

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