抗TRAF2, C-term抗体 | Anti-TRAF2, C-term antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of human ovary lysate using GTX89120 TRAF2 antibody, C-term. Dilution : 0.1μg/mlLoading : 35μg protein in RIPA buffer
	IHC-P analysis of human kidney using GTX89120 TRAF2 antibody, C-term. Antigen retrieval : citrate buffer pH 6Dilution : 3.8μg/ml
	IHC-P analysis of human pancreas using GTX89120 TRAF2 antibody, C-term. Antigen retrieval : citrate buffer pH 6Dilution : 3.75μg/ml
	IHC-P analysis of human placenta using GTX89120 TRAF2 antibody, C-term. Antigen retrieval : citrate buffer pH 6Dilution : 3.75μg/ml

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製品情報

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.1-0.3μg/ml
IHC-P	3.75μg/ml
Note : IHC-P Human Kidney shows cytoplasm and select nuclear staining.

Not tested in other applications.

Calculated MW	56 kDa. ( Note )
Positive Control	The peptide used to generate this antibody is available for purchase (GTX89120-PEP).
Predict Reactivity	Mouse, Rat, Bovine, Dog(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Peptide with sequence C-KMEAKNSYVRDD, from the C Terminus of the protein sequence according to NP_066961.2.
Purification	Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Tnf Receptor Associated Factor 2 , Mgc:45012 , Rnf117 , Trap , Trap3 , Traf2
Background	The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript varia
Database	・ Gene ID: 7186 ・ UniProt: Q12933

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