抗ATG16L1, Internal抗体 | Anti-ATG16L1, Internal antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human skin using GTX88747 ATG16L1 antibody, Internal. Antigen retrieval : citrate buffer pH 6Dilution : 3.75μg/ml
	WB analysis of mouse brain lysate using GTX88747 ATG16L1 antibody, Internal. Dilution : 0.1μg/mlLoading : 35μg protein in RIPA buffer

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製品情報

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.01-0.1μg/ml
IHC-P	3.75μg/ml

Not tested in other applications.

Calculated MW	68 kDa. ( Note )
Positive Control	The peptide used to generate this antibody is available for purchase (GTX88747-PEP).
Specificity/Sensitivity	This antibody is expected to recognise both reported isoforms (NP_110430.5 and NP_060444.3).
Predict Reactivity	Rat, Dog(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Peptide with sequence C-KVEKVLSKQHSSSIN, from the internal region (near the C Terminus) of the protein sequence according to NP_110430.5; NP_060444.3.
Purification	Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Autophagy Related 16 Like 1 , Apg16L , Atg16A , Atg16L , Ibd10 , Wdr30 , Atg16L1
Cellular Localization	Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5.
Background	The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Database	・ Gene ID: 55054 ・ UniProt: Q676U5

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