抗SCO2抗体 | Anti-SCO2 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of HL-60 cell lysate using GTX85482 SCO2 antibody. Working concentration : (A) 1 and (B) 2 μg/ml
	IHC-P analysis of human liver tissue using GTX85482 SCO2 antibody. Working concentration : 20 μg/ml
	IHC-P analysis of human liver tissue using GTX85482 SCO2 antibody. Working concentration : 2.5 μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.5 - 2 μg/mL
IHC-P	2.5 μg/mL
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	30 kDa. ( Note )
Positive Control	HL60 Cell Lysate(GTX27914) , Human Liver Tissue Slide

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	SCO2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SCO2.The immunogen is located within the last 50 amino acids of SCO2.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	SCO cytochrome c oxidase assembly protein 2 , CEMCOX1 , ECGF1 , Gliostatin , MYP6 , PD-ECGF , SCO1L , TP , TYMP , TdRPase
Cellular Localization	Mitochondrion inner membrane
Background	Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.
Database	・ Gene ID: 9997 SCO2 ・ UniProt: O43819 SCO2

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