抗PD-L2抗体 | Anti-PD-L2 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of mouse brain tissue using GTX85449 PD-L2 antibody. Working concentration : 2.5 μg/ml
	WB analysis of Raji cell lysate using GTX85449 PD-L2 antibody. Working concentration : 0.5 and 1 μg/ml
	IHC-P analysis of mouse brain tissue using GTX85449 PD-L2 antibody. Working concentration : 20 μg/ml
	IHC-P analysis of mouse brain tissue using GTX85449 PD-L2 antibody. Working concentration : 2.5 μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.5 - 1 μg/mL
IHC-P	2.5 μg/mL
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	31 kDa. ( Note )
Positive Control	Raji Cell Lysate(GTX27908) , Mouse Brain Tissue Lysate(GTX27934)

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	PD-L2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PD-L2.The immunogen is located within amino acids 140 - 190 of PD-L2.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	programmed cell death 1 ligand 2 , B7DC , Btdc , CD273 , PD-L2 , PDCD1L2 , PDL2 , bA574F11.2
Background	Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Database	・ Gene ID: 80380 PDCD1LG2 ・ UniProt: Q9BQ51 PDCD1LG2

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