抗DCLK1抗体 | Anti-DCLK1 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of mouse brain tissue using GTX85008 DCLK1 antibody. Working concentration : 20 μg/ml
	IHC-P analysis of mouse brain tissue using GTX85008 DCLK1 antibody. Working concentration : 5 μg/ml
	WB analysis of rat brain tissue lysate using GTX85008 DCLK1 antibody. Working concentration : (A) 1 and (B) 2 μg/ml
	IHC-P analysis of rat brain tissue using GTX85008 DCLK1 antibody. Working concentration : 2.5 μg/ml
	WB analysis of human brain tissue lysate using GTX85008 DCLK1 antibody. Working concentration : (A) 0.5 and (B) 1 μg/ml

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	0.5 - 1 μg/mL
IHC-P	2.5 μg/mL
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	82 kDa. ( Note )
Positive Control	Human Brain Tissue Lysate(GTX27918) , Rat Brain Tissue Lysate(GTX27942)

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PROPERTIES

Form	Liquid
Buffer	PBS with 0.02% sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	DCLK1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human DCLK1.The immunogen is located within the last 50 amino acids of DCLK1.
Purification	Purified by antigen-affinity chromatography
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	doublecortin like kinase 1 , CL1 , CLICK1 , DCAMKL1 , DCDC3A , DCLK
Background	DCLK1 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK1 mRNA, like that of the homologous DCLK2 and DCLK3, is highly expressed in adult brain, but only DCLK1 and DCLK2 transcripts are present in human fetal brain and the developing mouse embryo, suggesting that DCLK1 and DCLK2 may play roles in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a gene that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization. Unlike DCLK1, DCLK2 expression does not change in DCX- mice.
Database	・ Gene ID: 9201 DCLK1 ・ UniProt: O15075 DCLK1

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