抗CD26 [11D7]抗体 | Anti-CD26 [11D7] antibody

• 2025/11/04

  試薬 特別価格

  [GNT]一次抗体製品25％OFFキャンペーン[～2026/02/27]

  期間：2025/11/04 ～2026/02/27

  ダウンロード

  GeneTex International Corporation（GNT）

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of HEK293T cells transfected with CD26 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84602 CD26 antibody [11D7].Loading : 5 ug per lane
	IHC-P analysis of liver tissue using GTX84602 CD26 antibody [11D7].Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.Dilution : 1:50
	ICC/IF analysis of COS7 cells transiently transfected with CD26 plasmid using GTX84602 CD26 antibody [11D7].
	FACS analysis of HeLa cells using GTX84602 CD26 antibody [11D7].Red : Primary antibodyBlue : Negative control antibody

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	11D7
Isotype	IgG1
Application	WB, ICC/IF, IHC-P, FACS, ELISA
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500
ICC/IF	1:100
IHC-P	1:50
FACS	1:100
ELISA	Assay dependent

Not tested in other applications.

Calculated MW	88 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Full length human recombinant protein of human DPP4 (NP_001926) produced in HEK293T cell.
Purification	Purified by affinity chromatography From tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	dipeptidyl peptidase 4 , ADABP , ADCP2 , CD26 , DPPIV , TP103
Cellular Localization	Apical cell membrane,Cell junction
Background	Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Database	・ Gene ID: 1803 DPP4 ・ UniProt: P27487 DPP4

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Okondo MC et al. Nat Chem Biol 2016; (Epub) DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.	Application : ELISA

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