抗cK-Ras [234-4.2]抗体 | Anti-cK-Ras [234-4.2] antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	234-4.2
Isotype	IgG2a
Application	WB, IHC-P, IHC-Fr, IP
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

For IHC-Fr: Use at a concentration of 10 μg/ml. For IHC-P: Use at a concentration of 10 μg/ml. For IP: Use at an assay dependent dilution. For WB: Use at a concentration of 5 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW	22 kDa. ( Note )
Positive Control	SW480, Y1 cells, or normal skin tissue
Specificity/Sensitivity	This antibody reacts with cK Ras and vK Ras, and cross-reacts with cH Ras or cN Ras p21s in immunoblotting. For this reason we recommend a sample concentration step prior to immunoblotting; concentrate to 5 μg/ml with 1% gelatin as a stabilizer. For immunoprecipitation, use 5 μg per sample with 45 μl protein A agarose.

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PROPERTIES

Form	Liquid
Buffer	50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5, containing 0.09% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration	0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Rat
Immunogen	Recombinant fragment, corresponding to C terminal amino acids 54-189 of Rat cK RAS.
Purification	Purified IgG
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Kras Proto-Oncogene, Gtpase , C-K-Ras , Cfc2 , K-Ras2A , K-Ras2B , K-Ras4A , K-Ras4B , K-Ras , Ki-Ras , Kras1 , Kras2 , Ns , Ns3 , Rald , Rask2 , C-Ki-Ras2 , Kras
Background	This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 3845 ・ UniProt: P01116

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