抗PDGF Receptor beta [18A2] (PE)抗体 | Anti-PDGF Receptor beta [18A2] (PE) antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	18A2
Isotype	IgG1
Application	FACS
Reactivity	Human

目次に戻る

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
FACS	20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension

Not tested in other applications.

Calculated MW	124 kDa. ( Note )

目次に戻る

PROPERTIES

Form	Liquid
Buffer	PBS, 15mM sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	CD140b-transfected NIH 3T3 cells
Purification	Purified by size-exclusion chromatography
Conjugation	Phycoerythrin (PE)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR1,PDGFRB,PENTT,platelet derived growth factor receptor beta,PDGF Receptor beta,CD140b,PDGFR beta
Cellular Localization	Cell membrane,Cytoplasmic vesicle,Lysosome lumen
Background	The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Database	・ Gene ID: 5159 PDGFRB ・ UniProt: P09619 PDGFRB

目次に戻る