抗DR5 [DR5-01-1] (FITC)抗体 | Anti-DR5 [DR5-01-1] (FITC) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

DATA IMAGES

FACS analysis of CD262-transfectants using GTX80179 DR5 antibody [DR5-01-1] (FITC).

目次に戻る

製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	DR5-01-1
Isotype	IgG1
Application	FACS
Reactivity	Human

目次に戻る

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
FACS	Assay dependent

Not tested in other applications.

Calculated MW	48 kDa. ( Note )
Specificity/Sensitivity	This antibody recognizes an extracellular domain of TRAIL-R2 (DR5).

目次に戻る

PROPERTIES

Form	Liquid
Buffer	PBS, 15mM sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration	0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5.
Purification	Purified by size-exclusion chromatography
Conjugation	Fluorescein isothiocyanate (FITC)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	CD262,DR5,KILLER,KILLER/DR5,TNF receptor superfamily member 10b,TNFRSF10B,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9,TRAIL-R2
Cellular Localization	Membrane
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Database	・ Gene ID: 8795 TNFRSF10B ・ UniProt: O14763 TNFRSF10B

目次に戻る