抗CD13 [WM15] (APC)抗体 | Anti-CD13 [WM15] (APC) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

FACS analysis of human peripheral blood leukocytes using GTX74832 CD13 antibody [WM15] (APC).

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	WM15
Isotype	IgG1
Application	FACS
Reactivity	Human, Primate

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
FACS	10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension

Not tested in other applications.

Calculated MW	110 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS, 15mM sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Human AML cells
Purification	Purified by size-exclusion chromatography
Conjugation	Allophycocyanin (APC)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	ANPEP,APN,CD13,GP150,LAP1,P150,PEPN,alanyl aminopeptidase, membrane
Cellular Localization	Cell membrane
Background	Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 290 ANPEP ・ UniProt: P15144 ANPEP

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Haraguchi N et al. J Clin Invest 2010; 120 (9):3326-39 CD13 is a therapeutic target in human liver cancer stem cells.

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