抗p27 Kip1抗体 | Anti-p27 Kip1 antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P
Reactivity	Human

目次に戻る

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW	22 kDa. ( Note )

目次に戻る

PROPERTIES

Form	Liquid
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	A synthetic peptide derived from the C-terminal region of human p27kip1 protein.
Purification	Purified IgG
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	CDKN1B,CDKN4,KIP1,MEN1B,MEN4,P27KIP1,cyclin dependent kinase inhibitor 1B,p27 kip1
Cellular Localization	Nucleus,Cytoplasm,Endosome
Background	This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Database	・ Gene ID: 1027 CDKN1B ・ UniProt: P46527 CDKN1B

目次に戻る