抗Hice1 (phospho Ser 19/20)抗体 | Anti-Hice1 (phospho Ser 19/20) antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, ELISA
Reactivity	Human

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APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at a dilution of 1:100
For ICC/IF: Use at a dilution of 1:50
Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.

Calculated MW	48 kDa. ( Note )
Positive Control	HeLa , K562 , Blocking peptide (GTX70011-PEP)

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PROPERTIES

Form	Liquid
Buffer	1X PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic phosphopeptide (GTX70011-PEP) corresponding to the amino acids around Ser 19/20 conjugated to KLH
Purification	Affinity purified using antigen
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Haus Augmin Like Complex Subunit 8 , Dgt4 , Hice1 , Ny-Sar-48 , Haus8
Cellular Localization	Cytoplasm , Centrosome , Spindle
Background	HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM]
Database	・ Gene ID: 93323 ・ UniProt: Q9BT25

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Tsai CY et al. J Biol Chem 2011; 286 (34) : 30097-106 Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.	Application : WB, ICC/IF Reactivity : Human

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