抗ATG12 [EPR4800], C-term抗体 | Anti-ATG12 [EPR4800], C-term antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of lysates from (1) Apg12-transfected and (2) non-transfected 293T cells (10 μg per lane) using Apg12 antibody [EPR4800] at a dilution of 1:1,000.
	IHC-P analysis of human breast carcinoma using Apg12 antibody [EPR4800] at a dilution of 1:250.

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製品情報

Host	Rabbit
Clonality	Monoclonal
Clone Name	EPR4800
Isotype	IgG
Application	WB, ICC/IF, IHC-P
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW	15 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species	Human
Immunogen	Synthetic peptide corresponding to residues on the C-terminus in Human Apg12.
Purification	Tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Autophagy Related 12 , Apg12 , Apg12L , Fbr93 , Hapg12 , Atg12
Background	Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008]
Database	・ Gene ID: 9140 ・ UniProt: O94817

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Chung SD et al. PLoS One 2012; 7 (10) : e47299 Activating Nrf-2 signaling depresses unilateral ureteral obstruction-evoked mitochondrial stress-related autophagy, apoptosis and pyroptosis in kidney.

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