抗ROCK1 [1H4]抗体 | Anti-ROCK1 [1H4] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	WB analysis of HEK293 (1) and ROCK1 (AA: 403-610)-hIgGFc transfected HEK293 (2) cell lysate using GTX60535 ROCK1 antibody [1H4].
	WB analysis of human ROCK1 (AA: 403-610) recombinant protein using GTX60535 ROCK1 antibody [1H4].
	ELISA analysis of antigen using GTX60535 ROCK1 antibody [1H4]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	1H4
Isotype	IgG1
Application	WB, ELISA
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1/500 - 1/2000
ELISA	1/10000

Not tested in other applications.

Calculated MW	158 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS, 0.05% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Purified recombinant fragment of human ROCK1 expressed in E. Coli.
Purification	Protein G Purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Rho associated coiled-coil containing protein kinase 1 , P160ROCK , ROCK-I
Cellular Localization	Cytoplasm,Cytoplasm, cytoskeleton,Cell membrane
Background	This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 6093 ROCK1 ・ UniProt: Q13464 ROCK1

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