抗ABCG2 [1H2]抗体 | Anti-ABCG2 [1H2] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	ICC/IF analysis of HeLa cells using GTX60450 ABCG2 antibody [1H2].Green : ABCG2 Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments
	ELISA analysis of antigen using GTX60450 ABCG2 antibody [1H2]. Red : Control antigen 100ng Purple : Antigen 10ng Green : Antigen 50ng Blue : Antigen 100ng
	WB analysis of HepG2 (1), Cos7 (2), Jurkat (3) and NIH3T3 (4) cell lysate using GTX60450 ABCG2 antibody [1H2].

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	1H2
Isotype	IgG1
Application	WB, ICC/IF, ELISA
Reactivity	Human, Mouse, Monkey

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1/500 - 1/2000
ICC/IF	1/200 - 1/1000
ELISA	1/10000

Not tested in other applications.

Calculated MW	72 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Ascites, 0.03% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species	Human
Immunogen	Purified recombinant fragment of human ABCG2 expressed in E. Coli.
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , BCRP , BCRP1 , BMDP , CD338 , CDw338 , EST157481 , GOUT1 , MRX , MXR , MXR-1 , MXR1 , UAQTL1
Cellular Localization	Cell membrane
Background	The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Database	・ Gene ID: 9429 ABCG2 ・ UniProt: Q9UNQ0 ABCG2

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