抗VEGF Receptor 2 [8A01]抗体 | Anti-VEGF Receptor 2 [8A01] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Activation assay analysis of HUVECs stimulated with 20ng/ml VEGF or treated with 5.0 and 25 μg/ml GTX53464 VEGF Receptor 2 antibody [8A01] (30mins). Phospho-VEGFR2 was detected with IP-Western for P-Tyrosine.

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	8A01
Isotype	IgG1
Application	WB, IP, Activation
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
IP	Assay dependent
Activation	Assay dependent
Note : Activation This antibody can induce hVEGFR2 phosphorylation in HUVECs at > 5.0 μg/mL.

Not tested in other applications.

Calculated MW	152 kDa. ( Note )
Specificity/Sensitivity	This antibody recognizes hVEGFR-2 in western blot and immunoprecipitation assays. It shows no cross-reactivity with hVEGFR-1.

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PROPERTIES

Form	Liquid
Buffer	PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	hVEGFR2 N-terminal fragment (N30-200)
Purification	Protein G purified From tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	CD309,FLK1,KDR,VEGFR,VEGFR2,kinase insert domain receptor,VEGF Receptor 2
Cellular Localization	Cell membrane,Cytoplasm,Nucleus,Cytoplasmic vesicle,Early endosome,Cell junction,Secreted
Background	Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Database	・ Gene ID: 3791 KDR ・ UniProt: P35968 KDR

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