抗DR3 [1R12]抗体 | Anti-DR3 [1R12] antibody

• 特長
• 価格
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	1R12
Isotype	IgG1
Application	WB
Reactivity	Human

目次に戻る

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500 - 1:1000

Not tested in other applications.

Calculated MW	45 kDa. ( Note )

目次に戻る

PROPERTIES

Form	Liquid
Buffer	PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	500 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Human recombinant TNFRSF25 EC domain
Purification	Protein G purified From tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	APO3,DDR3,DR3,LARD,TNF receptor superfamily member 25,TNFRSF12,TNFRSF25,TR3,TRAMP,WSL1,WSLLR
Cellular Localization	Cell membrane,Secreted
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 8718 TNFRSF25 ・ UniProt: Q93038 TNFRSF25

目次に戻る