抗JNK (phospho Thr183)抗体 | Anti-JNK (phospho Thr183) antibody

• 2025/11/04

  試薬 特別価格

  [GNT]一次抗体製品25％OFFキャンペーン[～2026/02/27]

  期間：2025/11/04 ～2026/02/27

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  GeneTex International Corporation（GNT）

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Western blot analysis of SAPK/JNK phosphorylation expression in Anisomycin treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC
Reactivity	Human, Mouse, Rat

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APPLICATION

Application Note

WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW	48 kDa. ( Note )
Specificity/Sensitivity	This antibody is raised against JNK1/2 phosphorylated at Thr183. Based on sequence homology, it is predicted to react with JNK3 when phosphorylated at the corresponding residues - Thr221.

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PROPERTIES

Form	Liquid
Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	A synthesized peptide derived from human JNK around the phosphorylation site of Thr183
Purification	Antigen affinity purification
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Mitogen-Activated Protein Kinase 8 , Jnk , Jnk-46 , Jnk1 , Jnk1A2 , Jnk21B1/2 , Prkm8 , Sapk1 , Sapk1C , Mapk8
Background	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 5599 ・ UniProt: P45983

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