抗Cyclic nucleotide gated channel抗体 | Anti-Cyclic nucleotide gated channel antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Western blot of c-Nucleotide gated channel beta1 using GTX47900 with MCF-7 cell lysate. Apparent MW of CNGb is 160kDa.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Rat

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APPLICATION

Application Note

Optimal working dilutions should be determined experimentally be the end user.

Calculated MW	140 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Phosphate/Glycine, pH7.2-7.4
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Synthetic peptide
Purification	Affinity purified using antigen.
Conjugation	Fluorescein isothiocyanate (FITC)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Cyclic Nucleotide Gated Channel Beta 1 , Cncg2 , Cncg3L , Cncg4 , Cng4 , Cngb1B , Gar1 , Garp , Garp2 , Rcnc2 , Rcncb , Rcncbeta , Rp45 , Cngb1
Background	Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.
Database	・ Gene ID: 1258 ・ UniProt: Q14028

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