抗Fas Ligand [14C2] (PE)抗体 | Anti-Fas Ligand [14C2] (PE) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

FACS analysis of permeabilised Jurkat cells using GTX43177 Fas Ligand antibody [14C2] (PE).

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	14C2
Isotype	IgG1
Application	FACS
Reactivity	Human

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
FACS	Neat
Note : FACS The results may be optimized using membrane permeabilisation. Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Calculated MW	31 kDa. ( Note )
Specificity/Sensitivity	Clone 14C2 is reported to recognize a conformation dependent non-blocking epitope on CD178 (Daburon et al. 2013).

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PROPERTIES

Form	Liquid
Buffer	PBS, 0.09% Sodium Azide, 1% BSA, 5% Sucrose
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Purification	Protein G purified From tissue culture supernatant
Conjugation	Phycoerythrin (PE)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Fas Ligand , Alps1B , Apt1Lg1 , Aptl , Cd178 , Cd95-L , Cd95L , Fasl , Tnfsf6 , Tnlg1A , Faslg
Background	This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Database	・ Gene ID: 356 ・ UniProt: P48023

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