抗CD13 [WM15] (Low endotoxin, azide free)抗体 | Anti-CD13 [WM15] (Low endotoxin, azide free) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-Fr staining of human tonsil with Mouse anti Human CD13 antibody(GTX42441), clone WM15 (red in A) and Mouse anti CD21 antibody(GTX74728), clone LB21 (green in B). The merged image is in C with nuclei counterstained blue using DAPI. Low power.
	IHC-Fr analysis of human tonsil tissue using GTX42441 CD13 antibody [WM15] (Low endotoxin, azide free).
	IHC-Fr analysis of human tonsil tissue using GTX42441 CD13 antibody [WM15] (Low endotoxin, azide free).
	IHC-Fr staining of human tonsil with Mouse anti Human CD13 antibody(GTX42441), clone WM15 (red in A) and Mouse anti CD21 antibody(GTX74728), clone LB21 (green in B). The merged image is in C with nuclei counterstained blue using DAPI. High power.
	IHC-Fr staining of human tonsil with Mouse anti Human CD13 antibody(GTX42441), clone WM15 (red in A) and Mouse anti CD21 antibody(GTX74728), clone LB21 (green in B). The merged image is in C with nuclei counterstained blue using DAPI. Medium power.
	IHC-Fr analysis of human tonsil tissue using GTX42441 CD13 antibody [WM15] (Low endotoxin, azide free).
	IHC-Fr analysis of human tonsil tissue using GTX42441 CD13 antibody [WM15] (Low endotoxin, azide free).

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	WM15
Isotype	IgG1
Application	IHC-Fr, FACS, IP, ELISA, Functional Assay
Reactivity	Human, Rhesus Monkey

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
IHC-Fr	Assay dependent
FACS	1/50-1/100
IP	Assay dependent
ELISA	Assay dependent
Functional Assay	Assay dependent
Note : FACS Use 10μl of the suggested working dilution to label 106 cells or 100μl whole blood.

Not tested in other applications.

Calculated MW	110 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Human AML cells.
Purification	Protein A purified From tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Alanyl Aminopeptidase, Membrane , Apn , Cd13 , Gp150 , Lap1 , P150 , Pepn , Anpep
Background	Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 290 ・ UniProt: P15144

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Haraguchi N et al. J Clin Invest 2010; 120 (9):3326-39 CD13 is a therapeutic target in human liver cancer stem cells.	Application : FACS Reactivity : Human

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