抗NHE3抗体 | Anti-NHE3 antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

Western blot analysis of NHE3 in rat kidney tissues using a 1:1000 dilution of GTX41967.

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF
Reactivity	Mouse, Rat

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APPLICATION

Application Note

We recommend a working dilution of 1:1000 (WB).

Calculated MW	84 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Rabbit immunoglobulin in 50% glycerol
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Rat
Immunogen	AA809 to 831 of rat sequence
Purification	Affinity purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Solute Carrier Family 9 Member A3 , Nhe3 , Slc9A3
Cellular Localization	In intestinal epithelial cells, localizes to the ileal brush border.
Background	Sodium-hydrogen exchanger 3 (NHE3; Slc9a3) is an epithelial transport protein that carries out 1:1 exchange of Na+ and H+ across the plasma membrane. It is apically located in the prroximal tubule of the kidney, the thick ascending limb of the kidney, and in small intestine. NHE3 is phosphorylated and regulated by multiple kinases including PKA, SGK1 and CK2. It can be phosphorylated by calyculin A, and dephosphorylated by PP1 catalytic subunit in vitro.
Database	・ Gene ID: 24784 ・ UniProt: P26433

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Verta R et al. Int J Mol Sci 2019; 20 (10) Effect of Bilastine on Diabetic Nephropathy in DBA2/J Mice.
Hayasaki T et al. J Nutr Biochem 2019; 71 : 54-62 Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase.	Application : WB Reactivity : Mouse

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