抗CD68 [ED1]抗体 | Anti-CD68 [ED1] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-Fr analysis of rat lymph node tissue using GTX41868 CD68 antibody [ED1].
	IHC-Fr analysis of rat lymph node tissue using GTX41868 CD68 antibody (red n A) and Mouse anti Rat CD4 (Green in B). C is the merged image with nuclei counter-stained blue using DAPI. High power.
	IHC-Fr analysis of rat lymph node tissue using GTX41868 CD68 antibody (red n A) and Mouse anti Rat CD4 (Green in B). C is the merged image with nuclei counter-stained blue using DAPI. Low power.
	IHC-Fr analysis of rat lymph node tissue using GTX41868 CD68 antibody (red n A) and Mouse anti Rat CD4 (Green in B). C is the merged image with nuclei counter-stained blue using DAPI.Medium power
	IHC-Fr analysis of rat lymph node tissue using GTX41868 CD68 antibody [ED1].
	IHC analysis of rat liver, with induced hepatocellular damage tissue using GTX41868 CD68 antibody [ED1].
	IHC-Fr analysis of rat lymph node tissue using GTX41868 CD68 antibody [ED1].

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	ED1
Isotype	IgG1
Application	WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, RIA
Reactivity	Rat, Bovine

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent
IHC-Fr	Assay dependent
FACS	1/50-1/100
IP	Assay dependent
RIA	Assay dependent
Note : FACS Membrane permeabilisation is required for this application. Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Calculated MW	37 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	PBS, 0.09% Sodium Azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Rat
Immunogen	Rat spleen cells
Purification	Protein A purified From tissue culture supernatant
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	Cd68 Molecule , Gp110 , Lamp4 , Scard1 , Cd68
Background	This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 968 ・ UniProt: P34810

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Hou HH et al. Am J Physiol Lung Cell Mol Physiol 2018; (Epub) MMP-12 activates protease activated receptor (PAR)-1, upregulates placenta growth factor and leads to pulmonary emphysema.
Mukwaya A et al. Angiogenesis 2018; (Epub) Time-dependent LXR/RXR pathway modulation characterizes capillary remodeling in inflammatory corneal neovascularization.	Application : IHC-P Reactivity : Rat
Jeuthe S et al. J Cardiovasc Magn Reson 2016; 18 : 19 Myocardial T1 maps reflect histological findings in acute and chronic stages of myocarditis in a rat model.	Application : IHC-P Reactivity : Rat
Tsutsumi K et al. JPS 2016; (Epub) polaprezinc reduces *-induced peripheral neuropathy in rats without affecting anti-tumor activity.	Application : IHC-Fr Reactivity : Rat
Schmerler P et al. Acta Physiol (Oxf) 2014; Mortality and Morbidity in Different Immunization Protocols for Experimental Autoimmune Myocarditis in Rats.	Application : IHC-P Reactivity : Rat

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